Devi B. Basnet

• A highly self-motivated Ph.D. graduate with proven expertise in molecular biology, antibody therapeutics development and cell line development. Good, clear communicator and leader. Fluent in English. Good communicator in Korean and Hindi. Strong interpersonal skills developed from extensive social exposure. High desire to work on research and development management in biopharmaceutical company. Experienced Senior research scientist with over 13 years of experience in Bio-pharmaceutical industry. Good reputation for resolving problems, good organizational and communication abilities, easily adaptable at leading the group work. Special expertise in the following areas:
• Molecular biology
• Stable cell line development
• Streptomyces genetics
• Antibody/protein engineering
• Phage/Yeast display technology
• Biosynthesis of secondary metabolites

I have been equally involved in social activities leading various science and technology based activities. I have proactively involved in establishing of major organization among Nepali communities that have been serving the society with its full capacity. Lead and organize national and international conferences participating in hundreds of experts on various disciplines. Lead charity program to rains over 0.1 million dollars in the pandemics.

• Founder Vice President | Non-resident Nepalese Association (NRNA) 2005 ~ 2007
• General Secretary | NRNA-NCC South Korea) 2007 ~ 2009
  · Member | International Coordination Council (NRNA-ICC) 2009 ~ 2013
• National Coordinator | Skill Knowledge and Innovation Task force (Play a key role in connecting and networking the professionals of Nepali communities around the world to communicate on skill, knowledge and innovation through various interactive programs) 2015 ~ 2017
• Coordinator Asia Pacific| 1st Global Knowledge Convention 2018 (Key player of the convention, chair the session)
• Member | International Coordination Council (NRNA-ICC) (Play key role in organizing 2nd Global Knowledge Convention in 2020 as member in stirring committee and lead in charity program to raise the fund to help Nepalese in and out in the pandemic) 2019 ~ 2021
• Chair, 1st Asia Pacific regional Knowledge Convention 2020 (Lead and organize the convention covering experts from around region and other part of the world in different disciplines) 2020
• Founder Vice President | Society of Nepalese Students in Korea (SONSIK) 2004
• Member | Advisory Board (Advise and involve various academic programs during the tenure) 2005 ~ 2011
• Editor-in Chief | SONSIK Journal (Initiator) 2010 ~ 2014
  General Secretary | ChemSA, Tribhuwan University 1998 ~ 1999

• Mo, SangJoon; Kim, Dong Hwan; Lee, Jong Hyun; Park, Je Won; Basnet, Devi et al. (2011) Biosynthesis of the Allylmalonyl-CoA Extender Unit for the FK506 Polyketide Synthase (PKS) Proceeds Through a Dedicated PKS and Facilitates the Mutasynthesis of New Analogs, J. Am. Chem. Soc., 133 (4), pp 976–985.
• Basnet, D.B., Park, J.W. and Yoon, Y.J. (2008) Combinatorial biosynthesis of 5-O-desosaminyl erythronolide A as a potent precursor of ketolide antibiotics, J Biotech. 135 1, 92-96.
• Basnet, D.B., Oh, T.J., Hang, T.T.V., Sthapit, B., Liou, K., Lee, H.C., Yoo, J.C., and Sohng J.K. (2006) Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization, Mol. Cells, 22, 2, 154-162.Lee, S.K., Basnet, D.B., Hong, J. J., Jung, W.S., Choi, C.Y., Lee, H.C., Sohng, J. K., Ryu, K.G., Kim, D.J., Ahn, J.S., Kim, B.S., Oh, H.C., Sherman, D.H., Yoon, Y.J. (2005) Structural diversification of macrolactones by substrate flexible cytochrome P450 monooxygenases. Advanced Synthesis and Catalysis, 347, 1369-1378.
• Parajuli, N., Basnet, D.B., Chung, Y.S., Lee, H.C., Liou, K., and Sohng, J.K. (2005) Biochemical characterization of a Novel thermostable glucose-1-phosphate thymidylyltransferase from Thermus caldophilus: Probing the molecular basis from its unusual thermo stability. Enzyme and Microbial Technology, 37, 402-409.
• Basnet, D.B., Liou, K. and Sohng, J.K. (2005) Cloning of enediyne polyketide synthase gene clusters from Actinomadura verrucosospora ATCC 39334 as esperamycin producer; JBR 02, 02, 53~58.
• Basnet, D.B., Maharjan, J., Lee, H.C., Liou, K. and Sohng, J.K. (2005) Expression, characterization and modeling of glucose-1-phosphate thymidylyltransferase from Streptomyces ahromogenes var rubradiris NRRL 3061; JBR, 1,1; 1-8.
• Basnet, D.B., Sthapit, B.S., Lee, H.C., Liou, K., and Sohng, J.K. (2005) Swapping of domains in iterative type of PKS exemplifying with exchange of domain between NCS and AviM; 02, 01, 29-34.
• Kharel, M. K., Basnet, D.B., Lee, H.C., Liou, K., Woo, J.S., Kim, B.G., and Sohng, J.K. (2004) Isolation and characterization of the tobramycin biosynthetic gene cluster from Streptomyces tenebrarius. FEMS Microbiol Lett 230, 185-90.
• Lee, S.K., Basnet, D.B., Choi, C., Sohng, J.K., Ahn, J.S., and Yoon, Y. J. (2004) the role of erythromycin C-12 hydroxylase, EryK, as a substitute for PikC hydroxylase in pikromycin biosynthesis. Bioorg Chem 32,549-59.
• Kharel, M. K., Basnet, D.B., Lee, H. C., Liou, K., Moon, Y. H., Kim, J. J., Woo J. S., and Sohng, J.K. (2004) Molecular cloning and characterization of a 2-deoxystreptamine biosynthetic gene cluster in gentamicin-producing Micromonospora echinospora ATCC15835 Mol. Cells 18, 71-8.
• Kharel, M.K., Subba, B., Basnet, D.B., Woo, J.S., Lee, H.C., Liou, K., and Sohng, J.K. (2004) A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster. Arch Biochem Biophys 429, 204-14.
• Parajuli, N., Basnet, D.B., Kim, B.G., Lee, H.C., Sohng, J.K. and Liou, K. (2004) Diversity of Cytochrome P450 complement (CYPome) in Streptomyces peucetius ATCC 27952. Proceedings of Korean Society of Industrial Microbiology, Applied Chemistry. 8, 151-154.
• Parajuli, N., Basnet, D.B., Chan Lee, H., Sohng, J.K., and Liou, K. (2004) Genome analyses of Streptomyces peucetius ATCC 27952 for the identification and comparison of cytochrome P450 complement with other Streptomyces. Arch Biochem Biophys 425, 233-41.
• Basnet, D. B, Han S.J., Park, J.W., Yoon, Y.J. (2007) "Generation of Erythromycin A Intermediates by Deletion of eryBV and Enhancement of the Intermediates Production in Saccharopolyspora erythraea" The Korean Society for Microbiology and Biotechnology, June (Poster).
• Basnet, D. B., Park, J.W., Lee, S., Yoon, J., Yoo, Y.J., Park, H., Kim, E., Yoon, Y.J. (2007) "Combinatorial Biosynthesis of 5-O-desosaminyl erythronolide A as a Potent Precursor of Ketolide Antibiotics" The Korean Society for Bioengineering and biotechnology, Oct. (Poster).
• Basnet, D. B., Hang, T.T., Sthapit, B., Lee, H.C., Liou, K., and Sohng, J.K., (2004) "Molecular Cloning and Identification of a Biosynthetic gene cluster Of anguclyclines Sch 47554 and Sch 47555 produced from Streptomyces sp. SCC-2136 and heterologous expression of PKS genes." KSBB, proceeding of current Biotechnology of and Bioengineering (XV), 244-244. (Oral presentation).

· Basnet, D. B., Sthapit, B., Lee, H.C., Liou, K., and Sohng, J.K., (2004) An Unique Iterative Type I PKS, Neocarzinostatin Napthoate Synthase: Analysis and swapping of modules with AviM., The Korean Society of Industrial and Engineering Chemistry. (Oral presentation).