HOANG DAT NGUYEN
BUSAN
Summary
Research assistant in clinical pharmacology with 5 years experience. Mainly involved in study in which identify and investigate the effect of genetic factors on pharmacokinetics/pharmacodynamics of drug. Have expedience with handling clinical pharmacokinetics and pharmacodynamics data. Familiar with using statistical and PK/PD and other software to handle the genome data software: RStudio, Winnonlin, NONMEM, PLINK, Genome Studio, SNPTest.
Overview
4
4
years of professional experience
Work History
Research Assistant
Department of pharmacology and pharmacogenomics research center, Inje University College of Medicine
09.2018 - 03.2023
1) Involved in clinical pharmacogenetics study ( Prediction of warfarin steady state dose)
- Handle the clinical data including reviewing and cleaning clinical data,
- Analyze the effect of demographics, and clinical and genetic factors on the patient dose
- Develop statistical models to predict the patient dose based on the clinical and genetic factors
2) Involved in clinical pharmacogenomics study: (Discovery of genetic biomarker in association with the pharmacokinetics of the anti-Tb drugs in Korean Tb population, a genome-wide association study)
- Design the study
- Handle the patient concentration data: review and data cleaning
- Analyze patient pharmacokinetics study using the Population pharmacokinetics model.
- Develop the protocol to control for the quality of genome data, develop the protocol to impute the genome data, and analyze the association analysis
- Handle the patient genome study: Quality control analysis of genome data, Imputation of genome data.
- Analyze the genetic association analysis and interpret the result.
Education
Medical Doctor of Preventive Medicine
Hai Phong University of Medicine And Pharmacy
Hai Phong City, Viet Nam06.2018
Skills
- Pharmacokinetics analysis, Biostatistical analysis
- R studio, Winnonlin, NONMEM
- Genome studio, PLINK, ShapeIT, Impute2, SNPtest
- Word, PowerPoint, Excel
Accomplishments
Article: Comparison of multivariate linear regression and a machine learning algorithm developed for prediction of precision warfarin dosing in a Korean population. J Thromb Haemost. 2021 Jul;19(7):1676-1686. Epub 2021 Apr 21. PMID: 33774911
Conference paper: Pharmacogenomic variations associated with drug response of rifampin in a Korean patient. APSR 2022 conference, November 2022.
IELTS: 6.5, 2018
Timeline
Research Assistant
Department of pharmacology and pharmacogenomics research center, Inje University College of Medicine
09.2018 - 03.2023
Medical Doctor of Preventive Medicine
Hai Phong University of Medicine And Pharmacy
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