Summary
Overview
Work history
Education
Skills
Accomplishments
Certification
Languages
Timeline
AdministrativeAssistant
Shameer Pillarisetti

Shameer Pillarisetti

Gwangju,South Korea

Summary

Experienced and knowledgeable in nanomedicine with a strong foundation in scientific research methodologies and a keen interest in applying them to develop innovative solutions in healthcare. Proven expertise in nanomaterial synthesis, characterization techniques, Immunotherapy, bioinformatics, cheminformatics, and gene and protein engineering. Adept at designing and conducting experiments, analyzing data, and interpreting results. Demonstrated skills in scientific writing, critical thinking, and problem-solving. Collaborative team members actively contribute to interdisciplinary projects and possess a strong commitment to advancing scientific knowledge in the field of nanomedicine.

Overview

12
12
years of professional experience
12
12
years of post-secondary education
1
1
Certification

Work history

Postdoctoral research

National Immunotherapy Innovation Center, NIIC
09.2023 - Current
  • Developing the intranasal nanovaccine's for pre-clinical evaluation
  • In order to identify the appropriate antigen through computational biology and develop the desired molecule for non-viral vaccinations through genetic engineering and protein engineering.

Researcher

06.2017 - 08.2017
  • Contributed to ongoing projects and acquired valuable research methods knowledge from the research group before embarking on the Ph.D
  • Program.

Project Assistant

Nano Science and Technology
09.2016 - 05.2017
  • Created a hydrogel-based chitosan bandage that provides long-lasting release of Ayurvedic components from Indian traditional medicine, offering targeted pain relief when applied topically to affected area
  • Conducted clinical trials, leading to the implementation of the product for pain management among patients.

Andhra University
Visakhapatnam
02.2013 - 08.2013
  • Designed and constructed an online database utilizing MySQL and PHP, specifically focused on cataloging, and organizing marine secondary metabolites for comprehensive research and analysis.

Jr. Application Scientist

04.2012 - 09.2012
  • Assisted in development and testing of scientific applications and collaborated with cross-functional teams
  • Conducted experiments, analyzed data, troubleshooted technical issues, and supported customer inquiries to ensure successful implementation and utilization of scientific technologies
  • Utilized diverse array of bioinformatics and cheminformatics tools, such as GROMACS, Autodock, KNIME, ZincPharmer, Q-site Finder, and numerous others, for comprehensive analysis of scientific data.

Trainee

09.2011 - 03.2012
  • Developed the JAVA-based "BiospecApplications" application, specifically designed for small molecule analysis, enabling efficient and streamlined processing of data in the biospecification field.

Education

Ph.D. - Biomedical Sciences

Chonnam National University
Gwangju, South Korea
09.2017 - 08.2023

M.Tech - Nano Science and Technology

Amrita Vishwa Vidyapeetham
Cochin, Kerala, India.
06.2014 - 08.2016

B.E - Bioinformatics

Vinayaka Mission University
Salem, Tamilnadu, India.
08.2006 - 05.2010

Skills

Microscopy techniques- Cell and tissue-based assays with Inverted light microscopy, and fluorescence microscopy

Immunological techniques- Cell induction isolation, ELISA, fluorometric assay, isolation of primary immune system cells from animals, cell culture, etc

Histopathology techniques- Tissue fixation, Microtome, staining, Immuno-histological staining, etc

Animal cell culture- Maintain, subculture, freezing, thawing, revival, cell toxicity and specific induction of cell lines cryogenic storage, cell-based assays, and organ-based primary cell culture

Flow cytometry techniques- Apoptosis, Protein expression, cell population after induction and treatment Differential fluorescence staining procedures

Animal handling- Mouse and rat handling, Drug administration via intragastric incubation subcutaneous intraperitoneal and tail vein intravenous injection

Bioinformatics techniques- BLAST, KEGG, Phylogenetic analysis, Metagenomics, Whole-genome sequence (NGS) Primer designing

Blotting techniques- SDS page and Western blotting

Analytical techniques- High-Performance Liquid, Fourier Transform Infrared, Spectrophotometer, UV-VIS Spectrophotometer, Fluro Spectrophotometer, NMR, TEM, and SEM

Genetic engineering- Prokaryotic expression system cloning

protein engineering- Purification and production of proteins of interest

Statistical techniques- GraphPad Prism software

Coding basics- C, C, Java, Perl, Python, R, Linux Shell script

Accomplishments

1. Shameer Pillarisetti+, Vasukutty Arathy+, Jonghoon Choi, Shin Hyuk Kang, and In-Kyu Park (2023) "CXCR4 Targeting Nanoplatform for Transcriptional Activation of Latent HIV-1 Infected T Cells." ACS Applied Bio Materials, DOI: https://doi.org/10.1021/acsabm.3c00456. [+: Co-first authors]

2. Shameer Pillarisetti, Veena Vijayan, Jayakumar Rangasamy, Rizia Bardhan, Saji Uthaman, and In-Kyu Park (2023) "A Multi-Stimuli Responsive Alginate Nanogel for Anticancer Chemo-Photodynamic Therapy." Journal of Industrial and Engineering Chemistry, 123, 361-370, DOI: https://doi.org/10.1016/j.jiec.2023.03.053.

3. Shameer Pillarisetti+, Saji Uthaman+, Youn-Mook Lim, Jin-Oh Jeong, Rizia Bardhan, Kang Moo Huh, and In-Kyu Park (2023) "Light and immunostimulant mediated in situ re-education of tumor-associated macrophages using photosensitizer conjugated mannan nanoparticles for boosting immuno-photodynamic anti-metastasis therapy." Biomaterials Science 11, 1, 298-306, DOI: https://doi.org/10.1039/D2BM01508K. [+: Co-first authors]

4. Shammer Pillarisetti+, Jagannath Mondal+, Vijayabhaskarreddy Junnuthula, Monochura Saha, Seung Rim Hwang, In-kyu Park, and Yongkyu Lee (2023) "Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications." Journal of Controlled Release 353, 1127-1149, DOI: https://doi.org/10.1016/j.jconrel.2022.12.027. [+: Co-first authors]

5. Kangmin Noh, Saji Uthaman, Chung-Sung Lee, Yugyeong Kim, Shameer Pillarisetti, Hee Sook Hwang, In-Kyu Park, and Kang Moo Huh (2022) "Tumor intracellular microenvironment-responsive nanoparticles for magnetically targeted chemotherapy." Journal of Industrial and Engineering Chemistry, 111, 121-128, DOI: https://doi.org/10.1016/j.jiec.2022.03.042.

6. Shameer Pillarisetti+, Saji Uthaman+, Kang Moo Huh, Chong-Su Cho, and In-Kyu Park (2021) "Drug-dye-apoptosis inducing micelles for enhancing host immunity against advanced metastatic breast cancer by the combination of low dose chemotherapy and photothermal therapy." Journal of Industrial and Engineering Chemistry 97, 476-484, DOI: https://doi.org/10.1016/j.jiec.2021.03.003. [+: Co-first authors]

7. Saji Uthaman, Shameer Pillarisetti, Hye Suk Hwang, Ansuja Pulickal Mathew, Kang Moo Huh, Joon Haeng Rhee, and In Kyu Park (2021) "Tumor microenvironment regulating immunosenescence independent nanostimulant synergizing with near-infrared light irradiation for antitumor immunity." ACS Applied Materials & Interfaces 13, 4, 4844-4852, DOI: https://doi.org/10.1021/acsami.0c20063

8. Chanuk Jeong, Saji Uthaman, Babak Bagheri, Juwhan Kim, Shameer Pillarisetti, In-Kyu Park, and Yeu-Chun Kim (2021) "Self-assembled heptamethine cyanine dye dimer as a novel theranostic drug delivery carrier for effective image-guided chemo-photothermal cancer therapy." Journal of Controlled Release 329, 50-62, DOI: https://doi.org/10.1016/j.jconrel.2020.11.046.

9. Rimesh Augustine, Saji Uthaman, Nagendra Kalva, Kuen Hee Eom, Kang Moo Huh, Shameer Pillarisetti, In-Kyu Park, and Il Kim (2021) "Two-tailed tadpole-shaped synthetic polymer polypeptide bioconjugate nanomicelles for enhanced chemo-photothermal therapy." Polymer 230, 124061, DOI: https://doi.org/10.1016/j.polymer.2021.124061.

10. Manh-Cuong Vo, Seo-Yeon Ahn, Tan-Huy Chu, Saji Uthaman, Shameer Pillarisetti, Tung Nguyen Thanh Uong, Thangaraj Jaya Lakshmi, Mihee Kim, Ga-Young Song, Sung-Hoon Jung, Deok-Hwan Yang, Jae-Sook Ahn, Hyeoung-Joon Kim, In-Kyu Park and Je-Jung Lee (2021) "A combination of immunoadjuvant nanocomplexes and dendritic cell vaccines in the presence of immune checkpoint blockade for effective cancer immunotherapy." Cellular & Molecular Immunology 18, 6, 1599-1601, DOI: https://doi.org/10.1038/s41423-021-00666-z.

11. Yugyeong Kim, Saji Uthaman, Shameer Pillarisetti, Kangmin Noh, Kang Moo Huh, and In-Kyu Park (2020) "Bioactivatable reactive oxygen speciessensitive nanoparticulate system for chemo-photodynamic therapy." Acta Biomaterialia 108, 273-284, DOI: https://doi.org/10.1016/j.actbio.2020.03.027.

12. Shameer Pillarisetti+, Saji Uthaman+, Kang Moo Huh, Yang Seok Koh, Sangjoon Lee, and In-Kyu Park (2019) "Multimodal composite iron oxide nanoparticles for biomedical applications." Tissue Engineering and Regenerative Medicine 16, 451-465, DOI: https://doi.org/10.1007/s13770-019-00218-7. [+: Co-first authors]

13. Shameer Pillarisetti, S. Maya, S. Sathianarayanan, and R. Jayakumar (2017) "Tunable pH and redox-responsive drug release from curcumin conjugated γ-polyglutamic acid nanoparticles in cancer microenvironment." Colloids and Surfaces B: Biointerfaces 159, 809-819, DOI: 10.1016/j.colsurfb.2017.08.057

Book chapter

1. Shameer Pillarisetti, Veena Vijayan, Saji Uthaman, and In-Kyu Park. "Nanoplatforms for Anticancer Therapy Based on Reactive Oxygen Species." In Science and Applications of Nanoparticles, Jenny Stanford Publishing, pp. 103- 131.

Certification

  • Global Certification in RED HAT Linux operating system, Certification No.805010377556800.
  • Honored B grade in Indian National Cadet Corps (NCC) C certificate under Madras Regiment.

Languages

English
Fluent
Telugu
Native
Hindi
Intermediate
Tamil
Intermediate
Malayalam
Intermediate
Korean
Elementary

Timeline

Postdoctoral research

National Immunotherapy Innovation Center, NIIC
09.2023 - Current

Ph.D. - Biomedical Sciences

Chonnam National University
09.2017 - 08.2023

Researcher

06.2017 - 08.2017

Project Assistant

Nano Science and Technology
09.2016 - 05.2017

M.Tech - Nano Science and Technology

Amrita Vishwa Vidyapeetham
06.2014 - 08.2016

Andhra University
02.2013 - 08.2013

Jr. Application Scientist

04.2012 - 09.2012

Trainee

09.2011 - 03.2012

B.E - Bioinformatics

Vinayaka Mission University
08.2006 - 05.2010
Shameer Pillarisetti