SoJin Shin
Bupyeong,28
Summary
Hardworking and passionate job seeker with strong organizational skills eager to secure a GeneEdit's cell experimental screening researcher position. Ready to help team achieve company goals. master degrees with multidisciplinary research experiences in designing of biocompatibility and biodegradable polymers, nanoparticle, and biomedical applications. Specialized in developing drugs and gene delivery systems using polymer-based nanomaterials with cell membrane-based nanoparticles. Responsible, persistent, motivated, highly sociable, and experienced industry-academic cooperation research.
Overview
6
6
years of post-secondary education
Education
Master of Science - Bioengineering
Kangwon National University
Chuncheon, South Korea 09.2022 - 02.2024
Bachelor of Science - Bioengineering
Kangwon National University
Chuncheon, South Korea 03.2018 - 08.2022
Skills
1 Polymer synthesis
- methoxy poly(ethylene glycol)-block-poly(lactic acid) synthesis based on ring-opening polymerization
- Characterization – Proton nuclear magnetic resonance spectroscopy (1H NMR), Fourier transform infrared spectroscopy (FT-IR)
2 Nanoparticle formulation
- Formulation of polymeric nanoparticles based on thin filim hydration, precipitation, double emulsion method
- Formulation of hybrid polymersome based on nano-extrusion
- Modulation of mechanical properties – Drug release stability, drug loading efficiency
- Protein and DNA/protein/molecule encapsulation
- Characterization – Dynamic laser spectroscopy (DLS), nanoparticle tracking analysis (NTA), Zeta potential analysis (ELS), transmission electron microscopy (TEM), scanning electron microscopy (SEM), FRET assay
3 Nucleic acid handling and techniques
- Quantification and gel electrophoresis, mRNA transfection etc
4 Cell handling, cell membrane-based nanotechnology, in vitro experiment
- Cell handling – Madin-Darby Canine Kidney (MDCK), Vero, MCF-7, THP-1, MDA-MB-231, Raji, NK92MI, Raw 2647 etc
- Cell membrane-based nanotechnology – cell membrane purification, cell membrane vesicle formation, cell membrane-polymer membrane fusion and characterization (Western blot, FACS, CLSM, TEM, FRET assay)
- In vitro experiment - cell viability, cell uptake and mRNA transfection
- Bioimaging – Flow cytometry, Confocal microscopy
Patents
- Nanostructures Incorporating Polymersomes and Quantum Dots and Their Use in Virus Detection Methods (폴리머좀 및 양자점을 포함하는 나노구조체 및 이를 이용한 바이러스 검출 방법), 2023, PCT/KR2023/013654
- Amphiphilic Polymer-Incorporated Nanostructures for Virus Detection and Diagnostic Platform (양친매성 고분자를 포함하는 바이러스 검출용 나노구조체 및 이를 이용한 진단플랫폼), 2022, 10-2022-0184549
International Proceedings
- Eukaryote cell membrane-Polymersome hybrid nanoparticles for Advanced mRNA Delivery System, 10/2023, 2023 KSBB Fall meeting and International Symposium
- Development of NeuroFilament-Light chain Detection System using Anti-NFL Antibody Conjugated Quantum dot, 08/2023, SPIE Optics+Photonics
- Eukaryote cell membrane-based hybrid nanostructure systems for effective and advanced drug delivery system, 04/2023, 2023 KSBB Spring meeting and International Symposium
- Madin-Darby canine kidney cell membrane-based hybrid nanostructure system for effective detection of influenza virus,10/2022, 2022 KSBM Fall meeting and Symposium
Homepage
nbel2020.com
Publications
- Mammalian cell membrane hybrid polymersomes for mRNA delivery, 1st-Author, ACS applied materials & interfaces, Accepted (2024.04.03)
- Charge-Complementary Polymersomes for Enhanced mRNA Delivery, Co-Author, Pharmaceutics, Published (2023.12.15)
- Exosome Isolation Using Chitosan Oligosaccharide Lactate-1-Pyrenecarboxylic Acid-Based Self-Assembled Magnetic Nanoclusters, Co-Author, Advanced Healthcare Materials, Published (2024.03.02)
- Active-propulsion oral biomimetic delivery system for enhancing the mucosal immunity conferred by porcine epidemic diarrhea virus vaccine, Co-Author, Under Review
References
Prof. Hyun-Ouk Kim, Assistant Professor, Division of Chemical Engineering and Bioengineering, Kangwon National University, Republic of Korea, kimhoman@kangwon.ac.kr
Timeline
Master of Science - Bioengineering
Kangwon National University
09.2022 - 02.2024
Bachelor of Science - Bioengineering
Kangwon National University
03.2018 - 08.2022