CHANH-TRUNG NGUYEN
Summary
Biomedical engineer (Ph.D.) specializing in functional biomaterials, injectable hydrogels for tissue engineering, and therapeutic applications. Experienced in biomaterial synthesis, hydrogel development, 3D bioprinting, nanomaterials. Skilled in in vitro/in vivo evaluation, cell-based tissue models, and drug delivery systems with a strong publication record in leading journals.
Overview
11
11
years of professional experience
Work History
Postdoctoral Researcher
Medical Device Lab, University of Ulsan
09.2024 - Current
- Fabrication and Implantation of Artificial Liver for Tissue Engineering
- Led cross-functional research projects to develop innovative medical devices, enhancing product performance and user safety.
- Conducted extensive data analysis and interpretation to support regulatory submissions, ensuring compliance with industry standards.
- Collaborated with multidisciplinary teams to design and optimize experimental protocols, improving efficiency and reliability of outcomes.
- Mentored junior researchers in advanced research methodologies, fostering skill development and enhancing team productivity.
- Developed new protocols and improved existing laboratory processes.
- Published peer-reviewed articles detailing research findings, contributing to the advancement of knowledge in medical device technology.
- Engaged in grant writing and funding applications, successfully securing financial support for ongoing research initiatives.
- Contributed to high-impact publications by collaborating with fellow researchers and providing critical input.
- Designed effective experimental controls, ensuring robust conclusions from research studies.
- Contributed to and actively participated in research conception, design and execution to address defined problems.
Graduate Researcher
Medical Device Lab, University of Ulsan
03.2017 - 08.2024
- Synthesis of Erythropoietin Nanobots for Central Nervous System Injury
- Fabrication and Implantation of Artificial Blood Vessels
- Fabrication and Implantation of Artificial Liver for Tissue Engineering
Assistant Researcher
Photocatalysis Research Group, Ho Chi Minh City University of Technology
01.2015 - 02.2017
- Fabrication of Ag-, Cu-, Graphene-Modified TiO2 Nanotubes Based Photocatalysts for Water Treatment
- Synthesis of metal nanoparticles (Ag, Cu); metal oxides nanoparticles (SnO2, ZnO, TiO2)
Education
Ph.D. - Biomedical Engineering
University of Ulsan
South Korea09.2024
B.S. - Materials Science
Vietnam National University of Ho Chi Minh City
Ho Chi Minh City, Vietnam09.2016
Skills
Materials and devices
Natural biomaterials: Alginate, gelatin, fibrinogen, elastin, collagen, Matrigel
Decellularized tissue’s extracellular matrix: tendon, blood vessel, muscle, liver, kidney
Injectable hydrogels: formulation, crosslinking strategies, therapeutic encapsulation, and controlled release
Nanomaterial and composite material fabrication
Crosslinking chemistry (physical, chemical, enzymatic)
Fabrication system: Coaxial flow extruder, single & peristaltic pumping system
Custom devices: tubular and multi-core-shell scaffold generators
3D bioprinter
Thin-film/coating and nanoparticle system: Spin coater, Dry sprayer
Cell culturing techniques
Primary, stem cell culture
2D/3D/Mono-/co-culture system
Cell differentiation protocols
Pre-vascularization, angiogenesis models
In vivo implantation studies on mouse, rat
Material analysis
Chemical analysis: FT-IR, NMR, UV-Vis, HPLC, Raman
Morphological: TEM, SEM, AFM
Crystallinity & surface: XRD, XPS
Tissue engineering
Medical device development
Data analysis
Experimental design
Protocol development
Publication writing
Nanoparticle synthesis
Photocatalyst fabrication
Artificial blood vessels
Experimental controls
Problem resolution
Research strategy
Laboratory process optimization
Scientific writing
Computational skills
Research methodologies
References
- Kyo-in, Koo, Professor, kikoo@ulsan.ac.kr, University of Ulsan, Republic of Korea, Department of Electrical, Electronic and Computer Engineering
- Van Thuy, Duong, Ph.D., duong38@purdue.edu, Purdue University, West Lafayette, Indiana, USA, Weldon School of Biomedical Engineering
- Van Viet, Pham, Professor, pv.viet@hutech.edu.vn, Ho Chi Minh City University of Technology, Ho Chi Minh City, Vietnam, Advanced Materials and Applications Research Group
AWARDS AND SCHOLARSHIPS
Brain Korea 21 Fellowship for Leading Universities & Students from the Korean Government (BK21 PLUS), 2017-03 ~ 2024-03, Graduate Research scholarship, University of Ulsan, 2017-03 ~ 2024-09
PUBLICATIONS
- Journal Papers:
- C. T. Nguyen, V. P. Le, T. H. Le, J. S. Kim, S. H. Back, K. Koo
- “Sacrificing Alginate in Decellularized Extracellular Matrix Scaffolds for Implantable Artificial Livers”, Journal of Functional Biomaterials, vol. 16, Jan 19, 2025, DOI: 10.3390/jfb16010035. (Q1, IF: 5.2)
- V. T. Duong, T. T. Dang, V. P. Le, T. H. Le, C. T. Nguyen, H. L. Phan, J. Seo, C-C. Lin, S. H. Back, K. Koo
- “Direct Extrusion of Multifascicle Prevascularized Human Skeletal Muscle for Volumetric Muscle Loss Surgery”, Biomaterials, vol. 314, Sep 14, 2024, DOI: 10.1016/j.biomaterials.2024.122840. (Q1, IF: 12.9)
- V. T. Duong, C. T. Nguyen, H. L. Phan, T. T. Dang, C. Cha, S. H. Back, K. Koo
- “Double-layered Blood Vessels over 3 mm in Diameter Extruded by the Inverse-gravity Technique”, Biofabrication, vol.15, Sep 22, 2023, DOI: 10.1088/1758-5090/ac6ff. (Q1, IF: 8.0)
- C. T. Nguyen, V. T. Duong, C. H. Hwang, K. Koo
- “Angiogenesis in free-standing two-vasculature scaffold extruded by two-core-embedded device”, International Journal of Bioprinting, vol. 8, May 13, 2022, DOI: 10.18063/ijb.v8i3.557. (Q1, IF: 6.0)
- T. H. Le, C. T. Nguyen, K. Koo
- C. H. Hwang
- “Erythropoietin Nanobots: Their Feasibility for the Controlled Release of Erythropoietin and Their Neuroprotective Bioequivalence in Central Nervous System Injury”, Applied Sciences, vol. 12, Mar 25, 2022, DOI: 10.3390/app12073351. (Q2, IF: 2.5)
- C. T. Nguyen, C. R. Kim, T. H. Le, K. Koo
- “Magnetically guided targeted delivery of erythropoietin using magnetic nanoparticles”, Medicine, vol. 99, Mar 19, 2020, DOI: 10.1097/MD.0000000000010972. (Q2, IF: 1.4)
- C. H. Hwang, C. T. Nguyen, C.R. Kim, S. A. Mun, T. H. Le, K. Koo
- “Targeted delivery of erythropoietin combined with nanoparticles under magnetic guidance”, Journal of the Neurological Sciences, vol. 405, Oct 15, 2019, DOI: 10.1016/j.jns.2019.10.395. (Q2, IF: 3.2)
- P. V. Viet, C. T. Nguyen, M. N. Pham, V. H. Le, M. T. Cao
- “The fabrication of the antibacterial paste based on TiO2 nanotubes and Ag nanoparticles-loaded TiO2 nanotubes powders”, Journal of Experimental Nanoscience, vol. 12, Mar 14, 2017, DOI: 10.1080/17458080.2017.1301685. (Q2, IF: 2.8)
- Conference Papers and Presentations:
- C. T. Nguyen, T. H. Le, V. P. Le, M. Kim, J. Seo, K. Koo, “Feasibility of Liver dECM-Alginate Bio-ink in Co-Culture Conditions for 3D Liver Tissue Engineering Applications”, Biofabrication, Saskatoon, Canada, 2023
- C. T. Nguyen, V. P. Le, T. H. Le, M. Kim, J. Seo, K. Koo, “Bioinspired Liver dECM Scaffold using sacrificial Calcium Alginate for artificial Liver”, Biofabrication, Saskatoon, Canada, 2023
- C. T. Nguyen, T. H. Le, H. Lee, V. T. Duong, H. P. Nguyen, H. L. Phan, H. Son, S. Oh, S. Lee, K. Koo, C. H. Hwang, D. Cho, “Navigation of Drug Delivery Micro-robots by External Magnetic Field”, IFAC Conference on Marine Systems, Robotics, Daejeon, Republic of Korea, 2019
- C. T. Nguyen, H. P. Nguyen, V. T. Duong, H. L. Phan, T. H. Le, H. Son, H. Lee, S. Oh, S. Lee, C. H. Hwang, K. Koo, “Design and Simulation of Single Coaxial Microfluidic Device for Tubular Scaffold Formation”, EMBC, Berlin, Germany, 2019
- C. T. Nguyen, H. P. Nguyen, V. T. Duong, H. L. Phan, T. H. Le, H. Son, H. Lee, S. Oh, S. Lee, C. H. Hwang, K. Koo, “Formation of 280 �m Diameter Centerflow with Coaxial Microfluidic Device using Computational Fluid Dynamics”, EMBC, Berlin, Germany, 2019
- C. T. Nguyen, H. Lee, Y. Lee, V. T. Duong, H. L. Phan, C. H. Hwang, K. Koo, “Smaller alginate micro-droplets using three inlets microfluidic device for the drug delivery system”, EMBC, Honolulu, Hawaii, 2018
- C. T. Nguyen, V. T. Duong T. T. Dang, Y. Lee, H. L. Phan, H. Lee, C. H. Hwang, K. Koo, “Cell viability increasement of the alginate-gelatin scaffold”, EMBC, Honolulu, Hawaii, 2018
- C.T. Nguyen, V. H. Ta, M. T. Cao, V. V. Pham, “The methylene blue degradation ability of Cu2O nanoparticles loaded TiO2 nanotubes material”, The Conference on Science and Technology, Ho Chi Minh, Vietnam, 2016
RESEARCH INTERESTS
- Design and development of bioactive hydrogels and functional biomaterials for 3D tissue fabrication, regenerative medicine, and implantable devices.
- Stem cell–based tissue models and organoid engineering for disease modeling and therapy
- Controlled drug delivery systems using advanced biomaterials for targeted, and responsive therapeutic release.
- Vascularization and immune integration strategies to enhance the survival, maturation, and functionality of engineered tissues in vivo.
- Translational approaches in tissue engineering, bridging laboratory innovations to clinical solutions for organ replacement and regenerative therapies.
Timeline
Postdoctoral Researcher
Medical Device Lab, University of Ulsan
09.2024 - Current
Graduate Researcher
Medical Device Lab, University of Ulsan
03.2017 - 08.2024
Assistant Researcher
Photocatalysis Research Group, Ho Chi Minh City University of Technology
01.2015 - 02.2017
B.S. - Materials Science
Vietnam National University of Ho Chi Minh City
Ph.D. - Biomedical Engineering
University of Ulsan