YOUNGSEON CHOI
Yongin-si
Summary
Experienced multidisciplinary biomedical scientist with expertise in applied chemistry, molecular and cell biology, immunology, and nanotechnology. Offers over 20 years of R&D experience in academia, government research institutes, and drug discovery and pharmaceutical industry. Demonstrates a proven track record in conducting successful research and development projects, leading cross-functional teams, and delivering innovative solutions. Skilled in experiment design and execution, complex data analysis, and translating scientific findings into practical applications. Committed to advancing scientific knowledge and driving healthcare advancements through collaborative research and development efforts.
Overview
20
20
years of professional experience
Work History
Managing Director
Samsung Pharm Inc.
01.2024 - Current
- Directed integrated management of non-clinical, CMC, and clinical studies.
- Led translational research and clinical development planning (CDP), Target Product Profile (TPP), and Common Technical Document (CTD).
- Oversaw regulatory submissions and facilitated IND approval processes.
Managing Director
GemVax&Kael
01.2023 - 12.2023
- Managed R&D teams developing synthetic peptide-based therapies for neurodegenerative diseases including Alzheimer's Disease (AD) and Progressive Supranuclear Palsy (PSP).
- Advanced IND-enabling studies, securing FDA Phase 2 approval.
- Collaborated with academic and industry partners to streamline preclinical and clinical projects.
R&D Director
Biopharma Corp.
05.2020 - 12.2022
- Led mRNA vaccine development initiatives, delivering Phase 1 IND results.
- Secured government funding (~$8M) for advanced vaccine and therapeutic development.
- Directed cross-functional teams across drug discovery and biopharmaceutical innovations.
R&D Director
Neo-Nanomedics Korea Inc.
06.2018 - 03.2019
- Established R&D institute affiliated with the company
- Managed hyperthermia-based cancer therapy research and development using iron oxide nanoparticles and AC magnetic field generator
Consulting Team Leader
Clarivate Analytics
07.2017 - 01.2018
- Established open and professional relationships with team members to achieve quick resolutions for Scholarly Publication, Intellectual Property, and Life Sciences.
- Assisted in recruitment to build team of top performers.
- Delivered customized IP and research evaluation reports to drive strategic decisions.
R&D Director
GemVax&Kael Inc.
01.2015 - 06.2017
- Developed and validated immune-related in vitro/ex vivo assays (eotaxin Bioplex200 assay, T-cell proliferation), method transfer and coordinated the Central Lab operation in Ph.3 pancreatic cancer clinical trial in Korea
- Developed telomerase derived peptides screening strategy using in-house in vitro functional assays and outsourced CRO management to identify cosmetic functional peptides (anti-wrinkle, whitening, UV protection) and registered 4 peptides into ICID (Gemtide series)
- Designed and evaluated peptide drug formulation for improved PK (i.e
- LC/MS-based plasma stability test)
- Managed 10 outsourced non-clinical studies in Universities worldwide (UCLA, Univ
- Of Birmingham, Seoul National Univ., Hanyang Univ
- Etc.) for the indications including immune regulation, Alzheimer’s, rheumatoid arthritis, chronoid neovascularization, ototoxicity, benign hyperplasia, HIV/HBV/HCV, fibrosis, keloid, cancer etc
- Managed team works between R&D, Marketing, Clinical, IP, Strategic planning for novel business developments and business review
- Published GV1001 whitepapers and prepared IR materials
Research Professor
Yonsei University
01.2013 - 01.2015
- Developed MRI-based bioimaging sensor development and studied novel MRI sensor based on iron oxide nanoparticles’s magnetic resonance energy transfer
- Managed and worked with 2 Ph.D
- Students and 3 MS students for research and paper/proposal (Institute of Basic Science grant applications)
Senior Research Scientist
Institute Pasteur Korea
01.2006 - 01.2013
- Developed nanoparticles based bioimaging and sensing probe for target identification in early drug discovery and high content imaging applications
- Developed fluorescent probe for gene expression detection, real-time imaging and cellular analysis of cancer and Alzheimer’s, Malaria, Leishmania’s in cell-based drug screening applications
- Conducted LC-MS/MS based PAMPA/Caco-2 permeability test and in vitro genetic toxicity test (Ames, chromosome aberration, micronucleus) for screening preclinical drug candidate in HIV, HCV, Inflammation
- Published 14 SCI papers (1st author and corresponding author) and granted National Science Foundation (3 year, $150,000)
Postdoc
University of Florida
01.2005 - 01.2006
- Demonstrated high sensitivity electrochemical biosensor using polymer-based nanotube technology
Education
Ph.D. - Biomedical Engineering
University of Michigan
Ann Arbor, MI12-2005
M.S. - Industrial Chemistry
Hanyang University
01.1998
B.S. - Industrial Chemistry
Hanyang University
01.1994
Skills
- Cross-functional teamwork
- Project management
- Teamwork and collaboration
- Technical proficiency
- Product development
- Analytical skills
- Regulatory compliance
- Innovation management
- Intellectual property management
- Technical leadership
Projectmanagement
Over 19 years managed multidisciplinary research and development projects in nanoscience, chemical biology, drug discovery, and biopharmaceutical from design, execution, troubleshooting, and successful presentation of results., Developed and implemented synergistic collaborating skills through multidisciplinary training ranging from chemistry, biology, and biomedical engineering, Strong organizational ability and data presentation skills in clear and concise documentation of results and professional knowledge
Writing
Published 27 peer-reviewed manuscripts and 1 book chapter (provided upon request)., Wrote and received national research grant funding, Wrote and edited the Investment Relation (IR) materials for news publication
Leadershipandteamwork
Experienced in global communications and team work through serving various stakeholders in academia, industry and government research institute., Detail-oriented multidisciplined professional who is able to effectively work both independently and within a team environment
Majorpublications
- Recent advances in magnetic nanoparticle-based multi-modal imaging, 2015, Chem Soc Rev, 7, 44, 4501
- Fluorogenic Quantum Dots-Gold Nanoparticle Assembly for Beta Secretase Inhibitor Screening in Live Cells, 2012, Anal. Chem., 84, 20, 8595
- Intracellular protein target detection by quantum dots optimized for live cell imaging, 2011, Bioconjugate Chemistry, 22, 8, 1576
- Quantum dots: a tool for malaria drug screening, 2011, Malaria J., 10, 118
- Fluorogenic assay and live cell imaging of HIV-1 protease activity using acid-stable quantum dot-peptide complex, 2010, Chem. Commun., 46, 48, 9146
- In Situ Visualization of Gene Expression Using Polymer-coated Quantum Dots-DNA Conjugates, 2009, Small, 5, 2085
- Nanoparticles in Medical Diagnostics and Therapy, 2007, Nanotechnology in Biology and Medicine, CRC Press
- Synthesis and Functional Evaluation of DNA-Assembled Polyamidoamine (PAMAM) Dendrimers for Cancer Cell-Specific Targeting, 2005, Chemistry & Biology, 12, 35
- DNA-Directed Synthesis of Generation 7 and 5 Polyamidoamine (PAMAM) Dendrimer Nanoclusters, 2004, Nano Letters, 4, 3, 342
Awards
- World Technology Networks (WTN) Fellow, Materials/Nanotech, 2005
- ICI Student Award, Polymeric Materials Science and Engineering (PMSE) Division in American Chemical Society, 2006
Communication Skills
Excellent collaborating and understanding capability, negotiating skills with key opinion leaders and stakeholders in academia, industry, government through working experiences at various business sectors., Presented research work at major academic societies (American Chemical Society, Korea Chemical Society, IUPAC, Materials Research Society, Korea Biochip Society, Korea Oligonucleic acid society etc.), Received 1st standing in research presentation in ICI Student Award Competition (2006 Polymeric Materials Science and Engineering Division in American Chemical Society)
Timeline
Managing Director
Samsung Pharm Inc.
01.2024 - Current
Managing Director
GemVax&Kael
01.2023 - 12.2023
R&D Director
Biopharma Corp.
05.2020 - 12.2022
R&D Director
Neo-Nanomedics Korea Inc.
06.2018 - 03.2019
Consulting Team Leader
Clarivate Analytics
07.2017 - 01.2018
R&D Director
GemVax&Kael Inc.
01.2015 - 06.2017
Research Professor
Yonsei University
01.2013 - 01.2015
Senior Research Scientist
Institute Pasteur Korea
01.2006 - 01.2013
Postdoc
University of Florida
01.2005 - 01.2006
M.S. - Industrial Chemistry
Hanyang University
B.S. - Industrial Chemistry
Hanyang University
Ph.D. - Biomedical Engineering
University of Michigan
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